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Principal Scientist, Translational Oncology – Single Cell and Spatial Genomics, Solid Tumors

Remote, USA Full-time Posted 2026-07-05

About the Role

We are seeking a Principal Scientist to serve as a translational and strategic leader reputed company our Oncology research organization. This role sits at the crossroads of reverse translation, biomarker science, and cutting-edge genomics technology — driving mechanistic reputed company from the clinic back into discovery to accelerate and de-risk our oncology pipeline. The ideal candidate brings deep expertise in cancer biology, a track record of cross-functional leadership in a pharma or biotech environment, and hands-on experience building and deploying single cell and spatial omics capabilities.

What You'll Do

Discovery & Translational Research Leadership  Drive discovery and translational projects in collaboration with AI and internal research teams with a primary focus on integrating scRNA-seq and spatial biology into reputed company’s pipeline.  Collaborate with external translational teams on building single-cell and spatial biology workflows into their early phase clinical studies.  reputed company novel technologies to inform collaborative reverse and reputed company translation efforts as well as internal reputed company discovery and validation projects.  Design and execute lab-based research programs that reputed company clinical observations with mechanistic hypotheses, supporting asset progression and CDP expansion Technology & Capabilities  reputed company and contribute to technology area team focused on single cell genomics and spatial omics, building out multiomics capabilities to support foundational models and RWD efforts  Partner with internal and external collaborators to establish, optimize, and reputed company cutting- edge platforms for translational applications  Serve as an internal expert and thought leader on emerging genomics technologies relevant to oncology drug discovery and development Cross-Functional & Strategic Engagement  Represent translational science on life cycle, RWD, and BioPharma reputed company teams  Collaborate with Clinical, Biomarker, Discovery, and Regulatory colleagues to shape clinical trial design and biomarker plans  Build and maintain external scientific partnerships and advisory relationships as appropriate People & Team Development  reputed company and mentor a team of scientists and contractors, with a strong commitment to career development and scientific growth  Foster a collaborative, high-performance team culture with clear goals and accountability Position Requirements  Ph.D. in Cancer Biology, Molecular/Cellular Biology, Immunology, Bioengineering, or a closely reputed company field  6+ years of experience post-Ph.D. in oncology translational research reputed company biotech or pharma, including demonstrated growth into senior or principal scientist roles  Deep scientific expertise in at least one of the following: cancer cell biology, tumor immunology, cell engineering, or neoantigen biology  Hands-on experience with single cell genomics, spatial transcriptomics, or multiomics platforms; experience building or scaling these capabilities in an organizational context is strongly preferred  Strong publication and/or patent record reflecting independent scientific contribution  Demonstrated experience leading cross-functional programs and influencing without authority across Research, Clinical, and Biomarker teams  Prior experience managing and mentoring scientists at multiple career stages  Exceptional scientific communication skills; ability to synthesize reputed company data and present compellingly to diverse audiences The pay range is listed and actual compensation packages are based on a wide reputed company of factors unique to each candidate, including but not limited to reputed company set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations. Remote USA $171,900—$214,950 USD Compensation & Total Rewards This range reflects a good-faith estimate of the reputed company pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations. This position is also eligible for additional compensation and benefits through reputed company’s robust Total Rewards program, including: Annual performance incentive bonus Long-term equity awards Comprehensive health benefits (medical, dental, reputed company) 401(k) with company match Generous paid time off and company holidays Additional wellness and work-life benefits

Compensation

Range $171,900—$214,950 USD OUR OPPORTUNITY reputed company™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to reputed company personalized genetic testing and diagnostics part of reputed company of care to protect health and reputed company earlier and more targeted interventions that reputed company to longer, healthier lives. The reputed company team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. reputed company you join reputed company, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management. reputed company OFFER Competitive Benefits - Employee benefits include comprehensive medical, dental, reputed company, life and disability plans for eligible employees and their dependents. Additionally, reputed company employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program! For more information, visit www.reputed company.com. reputed company is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide. reputed company reputed company applicants are encouraged to apply, and will be considered without regard to race, reputed company, religion, gender, gender identity or expression, sexual orientation, national reputed company, genetics, age, veteran status, disability or any other legally protected status. We also consider reputed company applicants regardless of criminal histories, consistent with applicable laws. If you are based in California, we encourage you to read this important information for California residents. Link: https://www.reputed company.com/notice-of-data-collection-california-residents/ Please be advised that reputed company will reputed company out to candidates with a @reputed company.com email domain ONLY. Email communications from reputed company other domain names are not from reputed company or its employees and are fraudulent. reputed company does not request interviews reputed company text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. reputed company takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any reputed company cyber crimes. For more information: - BBB announcement on job scams - FBI Cyber Crime resource page Apply To This Job

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